IRC-083927 HCl

SKU: orb1741232

Description

IRC-083927 HCl is a novel colchicine-site microtubule polymerization inhibitor with potent in vitro anticancer activity in the low nanomolar range, including against taxane- and vinca-resistant cell lines. It demonstrates significant in vivo efficacy by orally inhibiting the growth of human cervical and breast cancer xenografts in mouse models, supporting its investigation for advanced, resistant cancers.

Key Properties

• CAS Number: 955082-09-4
• MW: 454.47
• Formula: C₂₂H₁₉FN₄O₄S
• SMILES: Cl.NS(=O)(=O)Nc1ccc(Oc2ccc(cc2)-c2cnc(COc3ccccc3)[nH]2)cc1F
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23654304