IRAK4-IN-28

SKU: orb1944281

Description

IRAK4-IN-28 (compound 42) is a potent, orally bioavailable IRAK4 inhibitor with an IC50 of 8.9 nM and a Kd of 0.58 nM. This research compound is used to investigate IRAK4 signaling in preclinical models of inflammatory and autoimmune disorders, both in vitro and in vivo.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2952532-92-0
• MW: 529.59
• Formula: C₂₇H₃₁N₉O₃
• SMILES: C(NC=1N=C(C=CC1)C=2C=NN(C)C2)(=O)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CCN(CC6)C7CC7
• Target: IRAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168476160