IRAK4-IN-16

SKU: orb1703354

Description

IRAK4-IN-16 is a potent and selective IRAK4 inhibitor with an IC50 of 2.5 nM. It demonstrates cytotoxic activity in vitro against several lymphoma and leukemia cell lines, including OCI-LY10 and TMD8 cells. This compound is a valuable chemical probe for researching IRAK4-dependent signaling in oncology and immunology.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1812188-83-2
• MW: 390.39
• Formula: C₁₇H₂₀F₂N₈O
• SMILES: C(NC=1C(C(F)F)=NN(C)C1)(=O)C2=C3N(N=C2)C=CC(N[C@@H]4CCCNC4)=N3
• Target: IRAK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

122196173