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IRAK inhibitor 6

SKU: orb1302082

Description

IRAK inhibitor 6 is a potent and selective small molecule targeting IRAK-4 kinase activity with an IC50 of 160 nM. It serves as a valuable research tool for investigating TLR/IL-1R signaling pathways in inflammatory and autoimmune diseases, applicable in both cellular and biochemical assays.

Research Area

Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number1042672-97-8
MW396.46
Purity99.44% (May vary between batches)
FormulaC20H20N4O3S
SMILESCOc1cc(ccc1NC(=O)c1csc(n1)-c1cccnc1)N1CCOCC1
TargetIRAK
SolubilityDMSO:8.57 mg/mL (21.62 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.26 mM)

Bioactivity

Target IC50
IRAK4:160 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, IL-1R associated kinase, Interleukin-1 receptor associated kinase, IRAK inhibitor 6, IRAK inhibitor6, IRAK inhibitor-6, IRAK, IRAK-4, inhibit

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

IRAK inhibitor 6 (orb1302082)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 170.00
1 ml x 10 mM (in DMSO)
$ 180.00
10 mg
$ 230.00
25 mg
$ 360.00
50 mg
$ 500.00
100 mg
$ 660.00
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