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IR-251

SKU: orb2278067

Description

IR-251 is a tumor-targeting NIR mitochondrial probe that disrupts mitochondrial function via OATP uptake and PPARγ inhibition. This induces ROS overproduction and suppresses β-catenin signaling, inhibiting tumor cell proliferation and metastasis in vitro and in vivo.

Research Area

Immunology & Inflammation, Metabolism Research, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetWnt/beta-catenin,Mitochondrial Metabolism,Others,Reactive Oxygen Species,PPAR
Molecular Weight886.48
FormulaC51H70BrClN4O2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information