Ipragliflozin

SKU: orb1305560

Description

Ipragliflozin (ASP1941) is a selective SGLT2 inhibitor used in research for Type 2 Diabetes Mellitus. It is applied in both in vitro binding assays and in vivo models to study glucose homeostasis and metabolic effects.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 761423-87-4
• MW: 404.45
• Purity: 99.38%
• Formula: C₂₁H₂₁FO₅S
• SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=4C(S3)=CC=CC4)=C(F)C=C2
• Target: SGLT
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.94 mM);DMSO:70 mg/mL (173.07 mM)

Bioactivity

• Target IC50:
  SGLT1 (human):1876 nM|SGLT1 (mouse):1380 nM|SGLT2:5.64 nM|SGLT1 (rat):1166 nM|SGLT2 (rat):6.73 nM|SGLT2 (human):7.4 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ASP 1941, ASP1941, ASP-1941, Ipragliflozin, Inhibitor, inhibit, Sodium-dependent glucose cotransporters, SGLT, SGLT2

Compound Identifiers

PubChem CID

10453870