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Ipatasertib-NH2

SKU: orb1988275

Description

Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for the target protein AKT used in PROTAC, binding to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 for AKT degradation.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1001382-14-4
MW415.92
FormulaC21H26ClN5O2
SMILESC[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CN)C4=CC=C(Cl)C=C4)=O)CC3
TargetOthers,Ligands for Target Protein for PROTAC

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Ipatasertib-NH2 (orb1988275)

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