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IOX5

SKU: orb3134171

Description

IOX5 is a selective prolyl hydroxylase (PHD) inhibitor with an IC50 of 0.19 μM for PHD2. In acute myeloid leukemia (AML) cells, IOX5 can stabilize HIF-1α, inhibit cell proliferation, and induce apoptosis. It exhibits anti-leukemia activity.

Research Area

Cell Biology, Epigenetics & Chromatin, Metabolism Research

Images & Validation

Key Properties

FormulaC17H19F3N4O2
TargetApoptosis,HIF/HIF Prolyl-Hydroxylase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information