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INY-05-040

SKU: orb2565959

Description

INY-05-040 is a potent, pan-AKT degrader that rapidly depletes all AKT isoforms, blocking downstream signaling and suppressing proliferation across a broad panel of cancer cell lines. Its utility extends to in vitro mechanistic studies and in vivo preclinical research targeting PI3K/AKT-driven cancers.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2503018-29-7
MW1026.77
FormulaC55H76ClN9O6S
SMILESC[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CNCCCCCCCCCCC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4)C(C)(C)C)=O)C7=CC=C(Cl)C=C7)=O)CC3
TargetPROTACs,Akt

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

INY-05-040 (orb2565959)

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