INY-03-041

• Catalog Number: orb1992823
• Category: Small Molecules
• Description: INY-03-041, a potent and highly selective PROTAC-based pan-AKT degrader, inhibits AKT1, AKT2, and AKT3 with IC50s of 2.0 nM, 6.8 nM, and 3.5 nM, respectively. This compound consists of the ATP-competitive AKT inhibitor GDC-0068 conjugated to Lenalidomide.
• Target: PROTACs
• MW: 798.41
• Formula: C₄₄H₅₆ClN₇O₅
• SMILES: O=C(C(N(CC1=C2C=CC=C1CCCCCCCCCCNC[C@H](C3=CC=C(Cl)C=C3)C(N4CCN(C5=C([C@H](C)C[C@H]6O)C6=NC=N5)CC4)=O)C2=O)CC7)NC7=O
• Storage: -20°C
• Research Area: Pharmacology & Drug Discovery
• Note: For research use only
• Expiration Date: 12 months from date of receipt.