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Lenalidomide-C9-aldehyde

Lenalidomide-C9-aldehyde

Catalog Number: orb1988267

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Product Properties
Catalog Numberorb1988267
CategorySmall Molecules
DescriptionLenalidomide-C9-aldehyde is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-C9-aldehyde can be used in the synthesis of a series of PROTACs, such as INY-03-041. INY-03-041 is a potent, highly selective and PROTAC-based pan-Akt degrader. INY-03-041 inhibits Akt1, Akt2 and Akt3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively.
TargetOthers
MW398.5
FormulaC23H30N2O4
SMILESO=C(C(N(CC1=C2C=CC=C1CCCCCCCCCC=O)C2=O)CC3)NC3=O
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
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