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| Catalog Number | orb1988267 |
|---|---|
| Category | Small Molecules |
| Description | Lenalidomide-C9-aldehyde is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-C9-aldehyde can be used in the synthesis of a series of PROTACs, such as INY-03-041. INY-03-041 is a potent, highly selective and PROTAC-based pan-Akt degrader. INY-03-041 inhibits Akt1, Akt2 and Akt3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively. |
| Target | Others |
| MW | 398.5 |
| Formula | C23H30N2O4 |
| SMILES | O=C(C(N(CC1=C2C=CC=C1CCCCCCCCCC=O)C2=O)CC3)NC3=O |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)