Interleukin-1β Convertase Substrate

SKU: orb2693984

Description

IL-1β converting enzyme (ICE, now called caspase-1), a cytosolic enzyme, is responsible for the cleavage of the inactive precursor protein to the active IL-1β. Similarly, caspase-1 hydrolyzes this 14-amino acid peptide that corresponds to the native cleavage site sequence around Asp11?-Ala11?. The peptide is also able to inhibit the cleavage of the precursor to the mature protein.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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Target	others
CAS Number	143305-11-7
MW	1584.71
Purity	≥95%
Formula	C₆₈H₁₀₅N₂₁O₂₃
Protein Sequence	NEAYVHDAPVRSLN

Storage & Handling

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Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Protocol Information

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