iNOS/TopoI-IN-1

SKU: orb2665480

Description

iNOS/TopoI-IN-1 (AuL9) is a dual-target inhibitor of Topoisomerase I (K_i=2.72 µM) and iNOS (K_i=1.49 µM), exhibiting anti-tumor activity in vitro against breast cancer cells (MCF-7 IC50=3.5 µM; MDA-MB-231 IC50=6.3 µM) by inducing DNA damage and apoptosis.

Research Area

Cell Biology, Immunology & Inflammation, Molecular Biology, Signal Transduction

Key Properties

• MW: 886.54
• Formula: C₃₄H₄₀AuBrCl₂N₃OS
• Target: Apoptosis|||NF-κB|||Topoisomerase|||NO Synthase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis|||NF-κB|||Topoisomerase|||NO Synthase