Inosine-5'-diphosphoric acid disodium salt

SKU: orb3180966

Description

Inosine-5'-diphosphoric acid disodium salt, as a decoy substrate for NM23-H2, exhibits excellent binding ability at the GDP-binding site of NM23-H2 with a dissociation constant (KD) of 5.0 μM. It can inhibit c-MYC transcription by disrupting the interaction between NM23-H2-Pu27-GQ, thereby inducing apoptosis and G2/M cell cycle arrest without affecting the kinase activity mediated by NM23-H2. Inosine-5'-diphosphoric acid disodium salt also possesses anti-hypoxic, antihypertensive, and antiarrhythmic activities, protects organisms from γ-radiation damage, and can be used in research on cancers such as Burkitt lymphoma and cardiovascular diseases.

Research Area

Cell Biology

Key Properties

• CAS Number: 54735-61-4
• MW: 472.15
• Purity: 99.93% (May vary between batches)
• Formula: C₁₀H₁₂N₄Na₂O₁₁P₂
• SMILES: O[C@H]1[C@H](N2C3=C(N=C2)C(N=CN3)=O)O[C@H](COP(OP([O-])([O-])=O)(O)=O)[C@H]1O.[Na+].[Na+]
• Target: Apoptosis,c-Myc

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,c-Myc