INI-4001

SKU: orb2665363

Description

INI-4001, a TLR7/8 agonist, exhibits EC50 values of 1.89 μM and 4.86 μM for TLR7 and TLR8, respectively. This compound induces signal transduction and SEAP production through TLR7 and TLR8. Furthermore, INI-4001 stimulates the production of high-affinity, fentanyl-specific antibodies, effectively preventing fentanyl from crossing the human blood-brain barrier. It serves as an effective adjuvant in anti-fentanyl vaccines for individuals with opioid use disorder (OUD).

Key Properties

• CAS Number: 2549050-07-7
• MW: 1141.5
• Formula: C₅₉H₁₀₉N₆O₁₃P
• SMILES: C(N1C=2C(NC1=O)=C(N)N=C(O[C@H](CCC)C)N2)C3CCN(CCOP(OCCOCCOCCOC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(=O)O)CC3

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only