Ingliforib

SKU: orb1298887

Description

Ingliforib (CP-368296) is a glycogen phosphorylase inhibitor developed for research. It exhibits antihyperglycemic effects by reducing hepatic glucose output and has demonstrated cardioprotective properties in experimental models, supporting investigations into diabetes and ischemia-reperfusion injury.

Research Area

Metabolism Research

Key Properties

• CAS Number: 186392-65-4
• MW: 457.91
• Purity: 99.60% (May vary between batches)
• Formula: C₂₃H₂₄ClN₃O₅
• SMILES: O[C@H]([C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)N1C[C@H](O)[C@H](O)C1
• Target: Phosphorylase,Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.74 mM);DMSO:125 mg/mL (272.98 mM)

Bioactivity

• Target IC50:
  GP (Brain):150 nM (IC50)|GP (liver):52 nM (IC50)|GP (muscle):352 nM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CP 368296, CP368296, CP-368296, inhibit, Inhibitor, Ingliforib, Glycogen phosphorylase (GP), GPi 296, GPi296, GPi-296

Compound Identifiers

PubChem CID

6451325