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Ingenol-5,20-acetonide
Catalog Number: orb1297585
| Catalog Number | orb1297585 |
|---|---|
| Category | Small Molecules |
| Description | Ingenol-5,20-acetonide |
| Purity | 98.69% |
| MW | 388.5 |
| CAS Number | 77573-43-4 |
| Formula | C23H32O5 |
| SMILES | [H][C@@]12OC(C)(C)OCC1=C[C@@]1([H])[C@H]3[C@@H](C[C@@H](C)[C@@]4(C=C(C)[C@H](O)C24O)C1=O)C3(C)C |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Ingenol-5,20-acetonide [orb1219415]
>98% (HPLC)
77573-43-4
388.5
C23H32O5
200 mg, 100 mg, 5 mg, 25 mg, 10 mg, 1 g, 500 mg, 50 mgIngenol-5,20-acetonide-3-O-angelate [orb1219417]
>98% (HPLC)
87980-68-5
470.6
C28H34O6
5 mg, 1 g, 10 mg, 500 mg, 200 mg, 25 mg, 50 mg, 100 mgIngenol-5,20-acetonide-3-O-angelate [orb1296059]
97.11%
87980-68-5
470.6
C28H38O6
10 mg, 100 mg, 50 mg, 25 mg, 5 mg, 1 mg, 1 ml x 10 mM (in DMSO)
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
