Influenza A virus-IN-14

SKU: orb3134418

Description

Influenza A virus-IN-14 (Compound 37) is an inhibitor of the influenza A virus (IAV), effectively suppressing H1N1 with an EC50 of 23 nM. It demonstrates low cytotoxicity, with a CC50 exceeding 100 μM, and reduces cytopathic effects while enhancing the survival rate of Calu3 cells. The compound exhibits synergistic effects with the neuraminidase inhibitor Oseltamivir. However, it shows poor pharmacokinetic properties in CD-1 mice.

Research Area

Infectious Disease & Virology

Key Properties

• Formula: C₂₂H₂₅F₃N₂O₄
• Target: Influenza Virus

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Influenza Virus