INF200

SKU: orb2277935

Description

INF200 (compound 5) is a sulfonylurea-based NLRP3 inflammasome inhibitor. In vitro, it reduces IL-1β secretion from human macrophages at 10 µM. In vivo, it improves cardiometabolic parameters, reduces systemic inflammation, and protects against cardiac dysfunction in a rat model of diet-induced metaflammation and ischemia/reperfusion injury.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• MW: 296.71
• Formula: C₁₃H₁₃ClN₂O₄
• Target: NOD-like Receptor (NLR),Pyroptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NOD-like Receptor (NLR),Pyroptosis