Indole-4-carboxaldehyde

SKU: orb1984117

Description

Indole-4-carboxaldehyde (ST-I4C) is a natural small molecule that mitigates methylglyoxal (MGO)-induced inflammatory responses in HepG2 cells. It functions by suppressing advanced glycation end-products (AGEs) and the expression of TNF-α and IFN-γ, while modulating the NF-κB pathway and glyoxalase-1. This compound is a useful research tool for studying oxidative stress, inflammation, and metabolic disorders in cellular models.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 1074-86-8
• MW: 145.158
• Purity: 98.89% (May vary between batches)
• Formula: C₉H₇NO
• SMILES: O=CC1=C2C=CNC2=CC=C1
• Target: COX,TNF,NF-κB
• Solubility: DMSO:40 mg/mL (275.56 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ST I4C, ST-I4C, Indole4carboxaldehyde, Indole-4-carboxaldehyde, Indole 4 carboxaldehyde

Compound Identifiers

PubChem CID

333703