Indium (III) thiosemicarbazone 5b

SKU: orb2283290

Description

Indium (III) thiosemicarbazone 5b is a cytotoxic agent effective against multiple cancer cell lines, including cisplatin-resistant MCF-7/DDP cells, by inhibiting PI3K/Akt/mTOR signaling and reducing P-gp. In vivo, it suppresses tumor growth in xenograft models, and liposomal formulations enhance its pro-apoptotic and autophagic activity, supporting its study in oncology and drug resistance research.

Key Properties

• CAS Number: 2345755-20-4
• MW: 425.04
• Formula: C₁₀H₁₅Cl₂InN₄OS
• SMILES: [OH](C)[In+3]12([Cl-])([Cl-])[N]=3C(C=[N]1N=C(N(C)C)[S-]2)=CC=CC3
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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