INCB 3284 dimesylate

SKU: orb1709418

Description

INCB 3284 dimesylate is a potent, selective, and orally active antagonist of the human CCR2 receptor, blocking MCP-1 binding with an IC50 of 3.7 nM. It has been utilized in research models of acute liver failure and inflammation, demonstrating efficacy in both in vitro cellular assays and in vivo preclinical studies.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 887401-93-6
• MW: 712.76
• Formula: C₂₈H₃₉F₃N₄O₁₀S₂
• SMILES: CS(=O)(O)=O.O[C@]1(C2=CN=C(OC)C=C2)CC[C@](N3C[C@@H](CC3)NC(CNC(C4=CC(C(F)(F)F)=CC=C4)=O)=O)([H])CC1.CS(=O)(O)=O
• Target: CCR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11679268