Imatinib Impurity E

• Catalog Number: orb1983311
• Category: Small Molecules
• Description: Imatinib Impurity E is a specific impurity found in Imatinib, an orally available inhibitor of multiple tyrosine kinases, including BCR/ABL, v-Abl, PDGFR, and c-kit. Imatinib (STI571) operates by semi-competitively inhibiting enzyme activity; it binds adjacent to the ATP binding site, inducing a closed or self-inhibited conformation. Additionally, Imatinib acts as an inhibitor against SARS-CoV and MERS-CoV.
• Target: Others
• MW: 873.02
• CAS Number: 1365802-18-1
• Formula: C₅₂H₄₈N₁₂O₂
• SMILES: N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=CC(NC(=O)C4=CC=C(CN5CCN(CC6=CC=C(C(NC7=CC(NC=8N=C(C=CN8)C=9C=CC=NC9)=C(C)C=C7)=O)C=C6)CC5)C=C4)=CC=C3C
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.