IL-17-IN-3

SKU: orb2945592

Description

IL-17-IN-3 (compound 11) is a potent small molecule inhibitor of IL-17A, demonstrating an IC50 of 35 nM. It has shown good tolerability in a rat model at doses up to 300 mg/kg/day for four days, supporting its utility for investigating IL-17-mediated pathways in both cellular and animal studies of autoimmune diseases.

Research Area

Immunology & Inflammation

Key Properties

• MW: 553.521
• Formula: C₂₂H₂₅F₆N₅O₃S
• SMILES: C1CC1/C=C(\C(=O)N[C@@H](C2CCC(CC2)(F)F)C(=O)NC3=NC=C(S3)CN4C[C@H](NC4=O)C(F)(F)F)/F
• Target: Interleukin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172643402