IKKß-IN-124

SKU: orb1737747

Description

IKKß-IN-124 is a selective allosteric inhibitor of IKKβ that stabilizes its inactive conformation, thereby preventing IκBα phosphorylation at Ser177/Ser181 and subsequent NF-κB activation. This compound is a valuable research tool for studying NF-κB signaling in cellular models of inflammation and oncology.

Key Properties

• CAS Number: 825608-40-0
• MW: 409.371
• Formula: C₁₇H₂₆Cl₂N₂O₃S
• SMILES: CCOC1=C(C=CC(Cl)=C1Cl)S(=O)(=O)NC1CC(C)(C)NC(C)(C)C1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

1257937