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IKK 16 hydrochloride

SKU: orb1707191

Description

IKK 16 hydrochloride is a potent small molecule inhibitor targeting IKK2, the IKK complex, and IKK1 with respective IC50 values of 40 nM, 70 nM, and 200 nM. It also inhibits LRRK2 (IC50: 50 nM). This compound is widely used in biochemical and cellular research to study NF-κB signaling and Parkinson's disease pathways in vitro.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1186195-62-9
MW520.09
FormulaC28H30ClN5OS
SMILESCl.O=C(NN1CCC(CC1)N1CCCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1
TargetLRRK2,Others,IκB/IKK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

IKK 16 hydrochloride (orb1707191)

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