II399

SKU: orb3133618

Description

II399 is a potent and selective dual-substrate inhibitor of NNMT, featuring an unconventional SAM mimic, with a Ki value of 5.9 nM. It exhibits a notable competitive inhibition pattern against NAM and can occupy both the substrate and cofactor binding pockets. II399 shows promise for research in cancer, metabolic, cardiovascular, and neurodegenerative diseases.

Key Properties

• CAS Number: 2928480-72-0
• MW: 481.93
• Formula: C₂₄H₂₄ClN₅O₄
• SMILES: O[C@H]1[C@H](N2C=3C(C=C2)=C(Cl)N=CN3)C[C@H](CN(CC#CC4=CC(C(N)=O)=CC=C4)C(C)=O)[C@H]1O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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