II-B08

SKU: orb1700359

Description

II-B08 is a cell-permeable small molecule inhibitor of SHP2 with an IC50 of 5.5 µM. It effectively suppresses growth factor-induced ERK1/2 phosphorylation and the proliferation of hematopoietic progenitor cells, making it a useful tool for studying oncogenic signaling pathways in both cellular and biochemical assays.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1143579-78-5
• MW: 557.6
• Formula: C₃₃H₂₇N₅O₄
• SMILES: CN1C(=C(C=2C1=CC(O)=C(C(O)=O)C2)C3=CN(CCC(NC4=CC=C(C=C4)C5=CC=CC=C5)=O)N=N3)C6=CC=CC=C6
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25262527