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IHMT-IDH1-053

SKU: orb2278427

Description

IHMT-IDH1-053 is a potent and selective irreversible inhibitor of the IDH1 R132H mutant, covalently binding at Cys269. It effectively suppresses 2-HG production in cells and inhibits the proliferation of IDH1-mutant cancer models, including fibrosarcoma and AML cells, making it a valuable tool for oncology research.

Research Area

Metabolism Research

Images & Validation

Key Properties

MW532.63
FormulaC25H33FN6O4S
TargetIsocitrate Dehydrogenase (IDH)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information