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IHMT-EZH2-426

SKU: orb2277691

Description

IHMT-EZH2-426 is a potent covalent degrader of EZH2, effective against wild-type and mutant forms with low nM IC50 values. It suppresses cancer cell proliferation in B-cell lymphoma and TNBC models by degrading EZH2 and reducing H3K27me3 levels, making it a valuable tool for epigenetic and oncology research.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

MW578.7
FormulaC31H35FN4O4S
TargetHistone Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information