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Catalog Number | orb1302153 |
---|---|
Category | Small Molecules |
Description | Iguratimod |
CAS Number | 123663-49-0 |
Purity | 99.96% |
MW | 374.37 |
SMILES | O=C1C=2C(=CC(NS(C)(=O)=O)=C(OC3=CC=CC=C3)C2)OC=C1NC=O |
Formula | C17H14N2O6S |
Biological Activity | Iguratimod (T614) is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 μM. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
123663-49-0 |
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