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Description
Research Area
Signal Transduction
Images & Validation
−
Key Properties
−| Source | E. coli |
|---|---|
| Biological Activity | The ED50 was determined by its ability to inhibit IGF - II induced proliferation of MCF - 7 is ≤ 0.3 μg/mL in the presence of 15 ng/mL of human IGF - II. |
| Target | IGFBP5 |
| Purity | Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
| Protein Sequence | MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS |
Storage & Handling
−| Storage | The lyophilized IGF-BP5 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IGF-BP5 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IGF-BP5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
|---|---|
| Form/Appearance | Lyophilized |
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−IBP5, IBP5, Insulin-like growth factor-binding protein 5, IBP-5
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Quick Database Links
UniProt Details
− No UniProt data available
NCBI Reference Sequences
−Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product| Protein | NP_000590.1 |
|---|
Protocol Information
Protein Handling and Storage Guide
Protein Handling Guide
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