IGF-1R modulator 1

SKU: orb2646233

Description

IGF-1R modulator 1 (Example 5) is a small molecule inhibitor of IGF-1R, FGFR1, TrkA, and TrkB with EC50 values ranging from 0.25 to 0.39 µM. It serves as a research tool for studying neurodegenerative conditions like Alzheimer's disease in both cellular and animal models of impaired neurotrophic signaling.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2375424-89-6
• MW: 387.39
• Formula: C₂₂H₁₇N₃O₄
• SMILES: O=C1NC(=O)N(C2=CC=C(OC=3C=CC=CC3)C(=C2)C)C(=O)N1C=4C=CC=CC4
• Target: EGFR,Trk receptor,IGF-1R

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139434107