IGF-1R inhibitor-3

SKU: orb2565978

Description

IGF-1R Inhibitor-3 (Compound C11) is a potent allosteric inhibitor of the insulin-like growth factor 1 receptor kinase, with an IC50 of 0.2 µM. This small molecule is a valuable research tool for studying IGF-1R signaling in cancer biology, applicable in both cellular and biochemical assays to investigate oncogenic pathways.

Research Area

Immunology & Inflammation; Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1227753-12-9
• MW: 482.55
• Formula: C₂₈H₂₇FN₆O
• SMILES: C(NC1CCN(CCCCC=2C=3C(NC2)=CC=C(C#N)C3)CC1)(=O)C4=C5C(C(C#N)=CN5)=CC(F)=C4
• Target: IGF-1R

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46927889