IETDC

SKU: orb3210631

Description

IETDC is a caspase 8 probe substrate. Upon activation, caspase 8 cleaves IETDC, releasing D-cysteine. The released D-cysteine can bind with HCBT to form luciferin in situ, which, along with H2O2-mediated release of 6-hydroxy-2-cyanobenzothiazole, produces a bioluminescent signal. IETDC is applicable in studies related to acute inflammation.

Key Properties

• Target: Caspase
• Molecular Weight: 741.81
• CAS Number: 1476735-95-1
• Formula: C₃₂H₄₇N₅O₁₃S
• SMILES: [C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)[C@H](CC)C)=O)(C(N[C@H](C(N[C@H](C(N[C@@H](C(O)=O)CS)=O)CC(OC)=O)=O)[C@@H](C)O)=O)CCC(OC)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase