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IDO1/TDO-IN-9

SKU: orb3136058

Description

IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO), with an IC50 value of less than 1 μM. It effectively inhibits the activity of IDO1 and TDO, preventing the degradation of tryptophan into kynurenine, thereby restoring immune activity in the tumor microenvironment and inhibiting tumor growth. IDO1/TDO-IN-9 shows potential for cancer research.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1878200-88-4
MW187.56
FormulaC6H3ClFN3O
SMILESFC1=CC2=C(N=C1Cl)ON=C2N
TargetIDO,Indoleamine 2,3-Dioxygenase (IDO)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information