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IDO1/TDO-IN-1

SKU: orb1688652

Description

IDO1/TDO-IN-1 (30) is a potent dual inhibitor of IDO1 (uncompetitive, Ki=0.23 µM) and TDO (competitive, Ki=0.73 µM). It has been shown to promote apoptosis in vitro, potentially through the mitochondria-mediated Bcl-2/Bax pathway, making it a useful tool for cancer immunology and cell death research.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number2379527-72-5
MW364.35
FormulaC21H16O6
SMILESO=C1C=2C(C3=C(C1=O)C(COC(C)=O)=CO3)=CC=C4C2C=CC(=O)C4(C)C
TargetIDO,Others,Indoleamine 2,3-Dioxygenase (IDO),Apoptosis,Bcl-2 Family

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information