IDO1-IN-30

SKU: orb3173524

Description

IDO1-IN-30 (Compound (R)-100) is a potent and highly selective inhibitor of IDO1. It exhibits an IC50 value of 4.8 nM against IDO1 in SKOV3 cells. In HepG2 cells, at a concentration of 25 µM, IDO1-IN-30 does not display significant cytotoxicity. Additionally, it eliminates inhibition of CYP450 enzymes, including 3A4, 2C9, and 2D6. This compound is suitable for research related to cancer and inflammatory diseases.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2581050-29-3
• MW: 398.37
• Formula: C₁₉H₁₆F₂N₆O₂
• SMILES: [C@@H](O)(C1=C(N=CC=2N1C=NC2)C3CC3)C4=CN(N=N4)C5=C(F)C=C(OC)C(F)=C5
• Target: Indoleamine 2,3-Dioxygenase (IDO),Cytochromes P450

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Indoleamine 2,3-Dioxygenase (IDO),Cytochromes P450