IDO1-IN-25

SKU: orb2665554

Description

IDO1-IN-25 is a dual IDO1/TDO2 inhibitor with IC50 values of 0.17 μM and 3.2 μM, respectively. It reduces LPS-induced NO production in RAW264.7 cells and exhibits in vivo anti-inflammatory activity in a croton oil-induced mouse ear edema model, supporting research in immunology and cancer immunotherapy.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2841467-86-3
• MW: 360.64
• Formula: C₁₄H₈Cl₃NO₂S
• SMILES: O=S(C1=NC=2C=C(Cl)C(Cl)=CC2O1)CC3=CC=C(Cl)C=C3
• Target: Indoleamine 2,3-Dioxygenase (IDO),IDO

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165390740