IDO-IN-13

SKU: orb1309555

Description

IDO-IN-13 (GS-4361) is a highly potent small molecule inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an EC50 of 17 nM. This compound is a valuable research tool for studying IDO1-mediated tryptophan metabolism in cancer immunology and inflammation, applicable in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2291164-02-6
• MW: 458.43
• Purity: 99.57% (May vary between batches)
• Formula: C₂₆H₁₇F₃N₄O
• SMILES: FC1=C(C=2N3C(C(=CC=C3)C=4C=C(C(NC5=CC=C(F)C=C5)=O)C(C)=NC4)=CN2)C=CC=C1F
• Target: IDO,Indoleamine 2,3-Dioxygenase (IDO)
• Solubility: DMSO:65 mg/mL (141.79 mM)

Bioactivity

• Target IC50:
  IDO1:17 nM(EC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Indoleamine 2,3-Dioxygenase, Indoleamine 2,3Dioxygenase (IDO), Indoleamine2,3Dioxygenase, Indoleamine2,3Dioxygenase(IDO), Indoleamine 2,3-Dioxygenase (IDO), inhibit, GS4361, GS-4361, GS 4361, IDOIN13, IDO-IN-13, IDO1, IDO IN 13, IDO, Inhibitor

Compound Identifiers

PubChem CID

137521135