IDN-7314

SKU: orb3211302

Description

IDN-7314 is a broad-spectrum caspase inhibitor with an IC50 ranging from 0.2 to 7 nM against all tested caspases. It effectively eliminates caspase-3/7 activity induced by Jo2. Additionally, IDN-7314 reduces procoagulant activity of tissue factor in hepatocytes. It is applicable in studies of chemically induced hepatitis, fulminant hepatic failure, and apoptotic liver damage.

Key Properties

• CAS Number: 254750-11-3
• MW: 549.38
• Formula: C₂₂H₁₇F₆N₃O₇
• SMILES: O(CC([C@@H](NC([C@@H](NC(C(NC1=C(F)C=CC=C1F)=O)=O)C)=O)CC(O)=O)=O)C2=C(F)C(F)=CC(F)=C2F
• Target: Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase