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ICI 204,448

SKU: orb2901474

Description

ICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes.

Images & Validation

Key Properties

CAS Number121264-04-8
MW501.83
Purity>98% (HPLC)
FormulaC23H27Cl3N2O4
SMILESCl.O=C(O)COC1=CC=CC(=C1)C(N(C(=O)CC2=CC=C(Cl)C(Cl)=C2)C)CN3CCCC3
TargetOpioid Receptor
SolubilityIn Vitro: DMSO : 125 mg/mL (249.09 mM; Ultrasonic )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • ICI 204,448 [orb1704477]

    >99.99% (May vary between batches)

    121264-04-8

    501.83

    C23H27Cl3N2O4

    5 mg, 1 mg, 10 mg, 25 mg, 50 mg
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Protocol Information

ICI 204,448 (orb2901474)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
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Available Sizes

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500 mg
2 mg
$ 120.00
5 mg
$ 160.00
10 mg
$ 240.00
25 mg
$ 370.00
50 mg
$ 540.00
100 mg
$ 750.00