Ibrutinib dimer

SKU: orb1992829

Description

Ibrutinib dimer is an impurity formed by the dimerization of Ibrutinib, a potent and irreversible Bruton's tyrosine kinase (Btk) inhibitor with an IC50 of 0.5 nM. This small molecule is widely used in biochemical and cellular research to investigate Btk signaling in oncology and autoimmune disease models, both in vitro and in vivo.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2031255-23-7
• MW: 880.99
• Formula: C₅₀H₄₈N₁₂O₄
• SMILES: N(CCC(=O)N1C[C@@](CCC1)(N2C=3C(C(=N2)C4=CC=C(OC5=CC=CC=C5)C=C4)=C(N)N=CN3)[H])C6=C7C(N(N=C7C8=CC=C(OC9=CC=CC=C9)C=C8)[C@]%10(CN(C(C=C)=O)CCC%10)[H])=NC=N6
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

68368145