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Iberdomide

SKU: orb1299503

Description

Iberdomide

Research Area

Immunology & Inflammation, Protein Biochemistry

Images & Validation

Key Properties

CAS Number1323403-33-3
MW449.5
Purity>98%
FormulaC25H27N3O5
SMILESO(CC1=CC=C(CN2CCOCC2)C=C1)C3=C4C(C(=O)N(C4)[C@@H]5C(=O)NC(=O)CC5)=CC=C3
TargetUbiquitin ligase
SolubilitySoluble in DMSO (up to at least 50 mg/ml)

Bioactivity

Target IC50
Cereblon:60 nM
In Vitro
Iberdomide has a greater potency for degrading the CRL4 complex substrates Ikaros and Aiolos (EC50s = 1 and 0.5 nM) but has no degradative activity for GSPT1 or CK1α.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CC-220
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Key Properties

No computed properties available.

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Protocol Information

Iberdomide (orb1299503)

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5 mg
$ 210.00
25 mg
$ 410.00
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