You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1700376 |
---|---|
Category | Small Molecules |
Description | IACS-010759 hydrochloride |
CAS Number | 1807523-99-4 |
Purity | 98.00% |
MW | 599.03 |
SMILES | Cl.O=S(=O)(C)C1CCN(C2=CC=CC(=C2)CN3N=C(N=C3C)C4=NC(=NO4)C=5C=CC(OC(F)(F)F)=CC5)CC1 |
Formula | C25H26ClF3N6O4S |
Biological Activity | IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NAD+ in immunoprecipitated complex I in low nM range. IACS-10759 shows significant efficacy in multiple tumor indications both in vitro and in vivo. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Filter by Rating