I942

SKU: orb1703369

Description

I942 is a selective acyclic nucleotide EPAC1 agonist used in cardiovascular research. It modulates inflammatory gene expression in vitro, such as in human umbilical vein endothelial cells, and inhibits pro-inflammatory cytokine signaling pathways relevant to atherosclerosis and vascular inflammation studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 868145-09-9
• MW: 369.43
• Purity: 99.86%
• Formula: C₂₀H₁₉NO₄S
• SMILES: O(CC(NS(=O)(=O)C1=C(C)C=C(C)C=C1)=O)C2=CC3=C(C=C2)C=CC=C3
• Target: cAMP,Others,Ras
• Solubility: DMSO:50 mg/mL (135.34 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

I942, I-942, I 942, EPAC1

Compound Identifiers

PubChem CID

2145430