FOG-001

SKU: orb2942752

Description

FOG-001 is a potent β-catenin/TCF interaction inhibitor (IC50 < 50 nM) that suppresses Wnt signaling, inhibits proliferation, and induces cell cycle arrest in vitro. It demonstrates significant anti-tumor efficacy in a COLO320DM colon cancer xenograft model, making it a valuable tool for studying oncogenic Wnt pathway mechanisms and therapeutic strategies.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• Target: Wnt/beta-catenin
• CAS Number: 3044032-95-0
• MW: 2076.39
• Formula: C₁₀₂H₁₃₄N₁₈O₂₅S₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Wnt/beta-catenin