I-49 free base

SKU: orb1298667

Description

I-49 free base is a novel benzylamino-substituted pyridopyrimidinone compound functioning as a potent and selective SOS1 inhibitor. It is utilized in biochemical and cellular research to investigate KRAS-driven signaling pathways and has demonstrated activity in both in vitro assays and in vivo cancer models.

Research Area

Signal Transduction

Key Properties

• MW: 482.92
• Purity: 99.88% (May vary between batches)
• Formula: C₂₃H₂₆ClF₃N₄O₂
• SMILES: Cl.C[C@@H](Nc1nc(C)nc2cc(=O)n(cc12)C1CCOCC1)c1cccc(c1C)C(F)(F)F
• Target: Raf
• Solubility: DMSO:22.5 mg/mL (46.59 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SOS1, I 49, I 49 free base, I49, I-49, I49 free base, I-49 free base

Compound Identifiers

PubChem CID

155977518