Hypothemycin

SKU: orb1707200

Description

Hypothemycin is a fungal polyketide that acts as a potent multikinase inhibitor, targeting VEGFR, MEK, FLT-3, PDGFR, and ERK with nanomolar to low micromolar affinity. It is widely used in biochemical and cellular research to study kinase signaling pathways in cancer and angiogenesis, with applications in both in vitro and in vivo experimental models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 76958-67-3
• MW: 378.37
• Purity: >98%
• Formula: C₁₉H₂₂O₈
• SMILES: COc1cc(O)c2c(c1)C1OC1CC(O)C(O)C(=O)\C=C/CC(C)OC2=O
• Target: Kinase
• Solubility: Soluble in DMSO (up to 10 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10270986