Hyodeoxycholic acid

SKU: orb1304791

Description

Hyodeoxycholic acid (NSC 60672) is a secondary bile acid investigated for its potential in managing hypercholesterolemia. Research applications include in vitro studies on lipid metabolism and in vivo models exploring its cholesterol-lowering effects and mechanisms.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 83-49-8
• MW: 392.57
• Purity: 97.26% (May vary between batches)
• Formula: C₂₄H₄₀O₄
• SMILES: [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C[C@H](O)[C@]2([H])C[C@H](O)CC[C@]12C
• Target: FXR,GPCR19,Endogenous Metabolite
• Solubility: DMSO:50 mg/mL (127.37 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:72 mg/mL (183.41 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.09 mM)

Bioactivity

• Target IC50:
  TGR5/GPCR19:31.6 µM(EC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

α-Hyodeoxycholic Acid, TGR5, inhibit, NSC 60672, NSC60672, NSC-60672, HDCA, Inhibitor, Hyodeoxycholic acid, G-protein coupled receptor 19, FXR, G protein-coupled Bile Acid Receptor 1, GPBAR1, GPCR19, Endogenous Metabolite, EndogenousMetabolite, alpha-Hyodeoxycholic Acid, a-Hyodeoxycholic Acid

Compound Identifiers

PubChem CID

5283820